ABI OMICSS Guide 2021
  • Welcome
  • Week 1
    • Molecular Biology
      • Introduction to Biology
      • Macromolecules
      • DNA & RNA
      • Cell Division
    • Command-Line
      • Connecting to the Server
      • The Linux Command-Line For Beginners
      • The Bash Terminal
    • R Programming
      • Getting Started
      • The Basics
      • Data Types
    • Week 1 Exam
  • Week 2
    • Molecular Biology
      • DNA Proofreading And Repair
      • Telomeres and Telomerase
      • Genes
      • The One Gene, One Enzyme Hypothesis
      • Transcription
      • Translation
    • R Programming
      • Data Types (continuation)
      • Reading Data
      • Subsetting
      • Control Structures
      • Functions
      • Scoping Rules
    • Week 2 Exam
  • Week 3
    • Molecular Biology
      • tRNA and Ribosomes
      • Stages of Translation & Protein Targeting
      • Heredity
      • Probabilities In Genetics
    • R Programming
      • Loop Functions
      • Base Graphics
    • Statistics and R
      • The Basics
    • Week 3 Exam
  • Week 4
    • Molecular Biology
      • Interesting Cases of Genes
      • The Chromosomal Basis of Inheritance
      • Variation in Species
      • Phenotype plasticity
    • R Programming
      • Practice 2
      • Practice 3
    • Statistics and R
      • Random Variables and Probability Distributions
      • Central Limit Theorem
    • Week 4 Exam
  • Week 5
    • Statistics and R
      • Confidence Interval
      • Introduction to Inference
      • t-distribution and Comparing Means
      • Linear Models
    • Experimental Techniques
      • Polymerase Chain Reaction (PCR)
      • Gel Electrophoresis
      • Sanger Sequencing
      • NGS Sequencing
    • Week 5 Exam
  • Week 6
    • Statistics and R
      • Power
      • ANOVA
      • Covariance and Correlation
    • NGS
      • Basic Unix Commands
      • Sequences and Genomic Features
      • FastQC
      • Practice Exercises
    • Week 6 Exam
  • Week 7
    • Statistics and R
      • Monte Carlo Simulation
      • Exploratory Data Analysis
      • Linear Regression
    • NGS
      • BEDtools
      • Alignment and Sequence Variation
      • Integrated Genomics Viewer
    • Week 7 Exam
  • Week 8
    • NGS
      • Variant Calling With GATK
      • Practice 1
    • Week 8 Exam
  • Module Syllabi
  • Additional Resources
  • Conclusion
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  • Pleiotropy and Lethal Alleles
  • Polygenic Inheritance and Environmental Effects
  • Gene Environment Interaction
  • Congratulations!

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  1. Week 4
  2. Molecular Biology

Interesting Cases of Genes

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PreviousMolecular BiologyNextThe Chromosomal Basis of Inheritance

Last updated 3 years ago

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Pleiotropy and Lethal Alleles

Pleiotropy is the concept of one gene affecting multiple characteristics. On the other hand, when an allele makes some genes nonfunctional, or causes them to take on an abnormal, harmful activity, then there is a good chance the allele is lethal. To delve deeper into this concept, read , and return here afterward.

Polygenic Inheritance and Environmental Effects

Human features like height, eye color, and hair color come in lots of slightly different forms because they are controlled by many genes, each of which contributes some amount to the overall phenotype. This is known as polygenic inheritance. Human phenotypes—and phenotypes of other organisms—also vary because they are affected by the environment. Read about the topic, and return here afterward.

Gene Environment Interaction

Not only do genes and environment affect our behavior, but their effect is also dependent on each other. Watch the video below to delve deeper into the topic.

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